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Chloramphenicol is an antibiotic first isolated from cultures of Streptomyces venequelae in 1947 but now produced synthetically.

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This includes meningitis, plague, cholera, and typhoid fever.

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Chloramphenicol acetyltransferase (or CAT) is a bacterial enzyme (EC that detoxifies the antibiotic chloramphenicol and is responsible for chloramphenicol.